%0 Electronic Article
%A Wang, Wei and Fan, Lijun and Li, Xuewen and Wang, Zirong and Zhou, Jianzhong and Jialengbieke, Buligen and Ren, Jianye and Hu, Xiaodong
%I Wiley
%D 2022
%D 2022
%G English
%@ 1365-2621
%@ 0950-5423
%~ Berufsakademien Sachsen - Bibliothek
%T Digestion of pectic polysaccharide from Brassica rapa L. in vitro and its effect on the intestinal microbiota in cyclophosphamide‐treated mice
%V 57
%J International Journal of Food Science & Technology
%V 57
%N 1
%P 92-100
%U http://dx.doi.org/10.1111/ijfs.15278
%X AbstractIn this study, the digestion of pectic polysaccharide from Brassica rapa L. (BRP) in vitro and its effect on the intestinal microbiota in cyclophosphamide (Cy)‐treated mice were investigated. As a result, the molecular weight (Mw) of BRP was significantly decreased after simulated gastrointestinal digestion, and content of reducing sugars (CR) was significantly increased (P < 0.05), implying that BRP was gradually degraded under gastrointestinal digestion conditions in vitro. In vivo, both 50 or 200 mg kg−1·BW/d of BRP significantly improved SCFAs concentrations that decreased by Cy treatment (P < 0.05). Meanwhile, BRP enriched the alpha‐diversity of intestinal microbiota and altered the microbial composition with an increase of Lactobacillus and a decrease of Clostridium, Ruminococcus, Oscillospira (P < 0.05). Besides, BRP intervention was conducive to the recovery of mouse body weight, thymus and spleen indices, and contributed to improve the intestinal barrier.
%Z https://katalog.ba-sachsen.de/Record/ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9pamZzLjE1Mjc4
%U https://katalog.ba-sachsen.de/Record/ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9pamZzLjE1Mjc4